I was happily exploring the Temple with my vampire Sim. She examined the traps and was left with two options. She aligned the Sun and caught fire. Not to worry there was pool near by and she had plenty of water in a waterfall bottles. Nope she was in full panic mode and nothing I could do would get her to extinguish herself. No water bottle and no jumping in the pool. So I exited without saving, lost all progress and reloaded my last save.
I found her inability to save herself in spit of my taking precautions to avoid this sort of thing mildly irritating.
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My sim got poisoned, and though I knew there was time, I made getting an antidote top priority. (It actually would be more exciting if the poison worked a tad quicker so there would be a sense of urgency and danger)
I have yet to get a curse. Care to share what happened to your Sims? I'd love to know.
the absolute first thing you need to do is pause the game. your sim is panicking, you are panicking. pause the game, take a deep breath, then click on your sim. there will be a self-interaction could 'put self out'. click on that, cancel their 'on fire' that is already queued up, unpause game, you now have a sim that will put themselves out and not burn up
edited to add replies to the later comments:
on poison, you have nearly an entire week to find the antidote. not even remotely a problem with that. the first stage is 12 hours long. when that runs out, they will either get better or enter stage two, which lasts 3 days. then, stage three hits, which is another 3 days. more than enough time to find a computer or some bone dust and visit a selvadoradan.
on curses, there are several guides about them. i put a quick one up in the 'jungle adventures did you know' thread, and simsvip has a much more in depth one as part of their overall guide to the pack